Enikő Krisch, Léa Messager, Benjámin Gyarmati, Valérie Ravaine, and András Szilágyi

Macromol. Mater. Eng. 2016, 301(3), 260–266

Nanogels loaded with fluorescent dextran as a model drug are synthesized by the oxidation induced cross-linking of water soluble redox responsive thiolated poly(amino acid) in miniemulsion without the introduction of any cross-linker molecule. Two types of high energy methods, namely, ultrasonication and high pressure homogenization (HPH), are compared. Dynamic light scattering and transmission electron microscopy measurements confirm that spherical nanogels in 100–150 nm diameter range are prepared successfully by HPH method. Size and surface charge of the nanogels can easily be controlled by environmental pH. The release of encapsulated drug is triggered by the degradation of nanogels in reducing environment due to the cleavage of disulphide bonds.

2015-20

Thumbnail N. Sojic, S. Arbault, L. Bouffier, A. Kuhn. Book Chapter in Luminescence in Electrochemistry Eds. F. Miomandre, P. Audebert. 2017. Pp. 257-291. Springer The great success of electrogenerated...
Thumbnail L. Bouffier, S. Arbault, A. Kuhn, N. Sojic Techniques de l’Ingénieur. 2018. P156 Les mesures sélectives et sensibles dans des échantillons complexes tels que l’urine ou le sang sont devenues des...
Thumbnail N. Sojic BOOK Royal Society of Chemistry Electrogenerated chemiluminescence (ECL) is a powerful and versatile analytical technique, which is widely applied for biosensing and successfully...
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Fibre-optic Biosensors
21 January 2013
Thumbnail Sojic N.,In Chemical Sensors and Biosensors, Eds. R. Lalauze and N. Jaffrezic-Renault, ISTE-Wiley, London, 2012. Book Chapter Technological needs for chemical, ionic and biological species...
Thumbnail Sojic N., Kuhn A.,Techniques de l’Ingénieur, Référence P150, 2012. Les capteurs sont devenus indispensables pour de nombreux aspects de notre vie, avec des exemples d’application allant de la...
Thumbnail Heim M., Kuhn A.,In Handbook of Electrochemistry, Springer, in press, 2013. Book Chapter In recent years, the field of highly ordered macroporous thin films coated onto solid electrode surfaces...